Ampelopsis Grossedentata Leaf Powder

Ampelopsis Grossedentata Leaf Powder – 98% Dihydromyricetin Standardized Extract 

Here are some of the most important specs:

• 98% dihydromyricetin is the active ingredient (HPLC confirmed).
• Advanced spray drying technology is used for production.
• Processing capacity: 50 tonnes or more per month with equal batch quality
• cGMP, FSSC22000, ISO9001, HACCP, HALAL, and KOSHER-approved quality system

Standard lead time is 10 days, and we have 500 kg or more ready to ship.

Since 2013, Shaanxi Zhenhuacui Biotechnology has been working with more than 200 nutrition and skincare brands in 35 countries to run one of the most advanced plant extract facilities in Asia, specializing in the production of Ampelopsis Grossedentata Leaf Powder and other high-quality botanical ingredients. Our dedicated 18-person research and development team (60 percent of our workforce) makes sure that every batch meets pharmaceutical-grade standards. They do this while keeping prices low by using vertically integrated supply lines that include organic farms in Hubei Province that we contract with and the final packing.

Business benefits that keep your supply line safe:

• ISO-certified production lines get rid of the risk of contamination.
• Buying raw materials from two different sources keeps the flow from stopping.
• Stability statistics from 24 months backs up longer product shelf life
• Regulatory paperwork package speeds up your entry into the market

Product Overview

In China's pristine Wuling Mountain area, high-altitude Ampelopsis grossedentata plantations (800–1200 m elevation) provide this standardised extract's constant bioactivity, which raw leaf powders can't match.

What's different about this ingredient:

The flavonoid primarily investigated for liver protection and metabolism, dihydromyricetin, is 98% pure in that light brownish-yellow powder. Pharmaceutical-grade crude extracts allow precise dosages and reduced material costs per serving than 10-15% crude extracts.

Thermal stability tests at 120°C for 30 minutes were successful. It can be baked, pasteurised, and compressed tablets. Small particle size (80–120 mesh) reduces sedimentation in liquors and water-based beverages for quick breakdown.

Formulation uses that have been approved by our customers:

• One of the biggest markets in Asia uses 200 mg per serve in hangover shots.
• Liver-supporting pills (works well with milk thistle)
• SPF moisturisers with antioxidants (stable in emulsions up to pH 7.5)
• Function candies without sugar that can withstand high temperatures for making hard sweets

Hepatoprotective ingredients with clean labels became 34% more popular among consumers in 2023 compared to the previous year (Innova Market Insights). At the point where traditional botanical knowledge meets current health trends, your goods will have this naturally occurring compound.

Product Features & Benefits

High Purity & Pharmaceutical-Grade Standardization

Triple HPLC tests are done on each batch (in-process, pre-release, and stability) to make sure that it has 98% ±2% Dihydromyricetin content. This accuracy gets rid of the batch-to-batch variation that is common in crude extracts. This protects your product claims and lowers the number of rejections by quality control.

Clinically Relevant Antioxidant Capacity

Independent lab tests show that DPPH radical scavenging power is higher than 92% at a dose of 50μg/mL. This is about the same as synthetic antioxidants like BHT, but it has a clean label appeal. This strength backs up claims of effectiveness in antioxidant-focused formulas.

Validated Thermal Stability

Studies that sped up the degradation process (120°C/30min) show less than 3% active loss, compared to 15-20% degradation in extracts that weren't optimised. You can use this stable data to back up claims about how long your product will last.

Regulatory-Ready Clean Label Profile

Heavy metals below EU limits (Pb <0.5ppm, As <0.3ppm), no pesticide residues found (450+ substances studied), and proof that the food is not genetically modified. This item comes with all the paperwork needed for FDA NDI reports and EU Novel Food applications.

Exceptional Solubility Across pH Ranges

In 5 minutes at room temperature, it dissolves fully in water (pH 4–8) and 40% ethanol liquids. Particle engineering stops sticking during high-speed mixing, which cuts down on the time it takes to process.

Multi-Pathway Health Benefits Backed by Research

Studies that were studied by experts show that it protects the liver (lowers ALT and AST levels), reduces inflammation (blocks the NF-κB pathway), and helps the body's glucose metabolism (makes insulin work better in animal models). These processes help with a number of different product positioning tactics.

Technical Specifications

Certificates of Analysis (COA) provided with every shipment.

Applications Across Industries

Functional Beverages (38% of client applications)

• Ready-to-drink health shots: 150–300 mg per dose to help with hangovers
• Mixes well with chrysanthemum and liquorice root in herbal tea mixes.
• Drinks for sports recovery: Antioxidant boost after working out (works with fluids)
• Water additives for detox: There is no cloudiness in the clear solution in cold water.
• Case study: A Japanese RTD brand with 200 mg per bottle had a 22% return buy rate.

Dietary Supplements (45% of client applications)

• Liver health capsules: 150 to 300 mg daily is the usual dose (standardised extract lowers pill count vs. crude powder).
• Hangover prevention tablets: quickly melting form for use before drinking
• Stacks with resveratrol, curcumin, and CoQ10 to make an antioxidant combination.
• Formulas that help the metabolism: Potential new uses for managing glucose

Functional Foods & Snacks

• Tonnes of heat won't hurt throat lozenges, so they can be used to make hard candies (the boiling sugar process works).
• Protein bars: Each dose has 1,500 ORAC units added without changing the taste.
• Powders for meal replacements: Taste that is neutral (no sharpness at less than 500 mg per dose)

Cosmetic & Personal Care

• Serums that fight ageing: Emulsions that are stable (checked in bases with pH 5.5 to 7.5)
• Suncare products: Use 1% to 3% of this ingredient in your formulas to boost antioxidant defence.
• Soothing creams: anti-inflammatory qualities for use on sensitive skin

Custom Combination Formulas

Popular synergistic mixes that were made for customers:

• Dihydromyricetin and Hovenia dulcis (better help for hangovers)
• Milk thistle and dihydromyricetin (complete liver defence)
• Dihydromyricetin + Monk fruit (system of antioxidants and sweeteners)

Quality Certifications

Our location has the widest range of certifications in the business, which makes sure that your goods meet all of the world's regulatory standards:

• cGMP stands for "Current Good Manufacturing Practice." These are FDA-approved rules for making medicines.
• Global food safety qualification called FSSC22000 is recognised in more than 150 countries.
• The international quality control method is called ISO9001:2015.
• HACCP stands for "hazard analysis for critical control points."
• HALAL: Approved by the Islamic Food and Nutrition Council of America
• Orthodox Union (OU) has certified that it is Kosher.
• Organic Certification—the same thing for organic product lines in the US and EU
• Non-GMO Verified: Tested and proven by a third party

Additional compliance documentation available:

• EU New dossiers on food safety
• Support for the US FDA NDI (New Dietary Ingredient) warning
• The China SC food production licence was given out in 2019.
• Certification as allergen-free (28 allergies checked)

Production Process Excellence

1. Raw Material Traceability

Contract organic farms in Hubei Province that are GAP-certified make it possible to track Ampelopsis Grossedentata Leaf Powder all the way from the field to the plant. The highest amount of Dihydromyricetin is found in fresh leaves harvested in the spring (March–April) used to produce this powder.

2. Advanced Extraction Technology

• Hot water extraction (80–95°C): Gets the most polyphenols out of the plant while avoiding harsh solvents
• Membrane filtering gets rid of impurities and concentrates bioactive chemicals.
• Cleaning with macroporous resin: 98% purity is reached through selective adsorption
• Spray drying (inlet 180°C, exit 80°C): Makes fine powder that flows easily.

3. Supercritical CO₂ Polishing (Optional)

For very clean uses (cosmetic grade), supercritical fluid extraction gets rid of any remaining waxes and colours, leaving behind a nearly white powder that is easier to dissolve.

4. Six-Stage Quality Control

• Testing of incoming raw materials (ID, strength, and toxins)
• Monitoring during the process (extraction rate, concentration)
• Testing before the release (full standard panel)
• Verification of stability (faster and real-time studies)
• Validation of microbes (sterility for certain uses)

5. Cleanroom Packaging

To keep things clean after production, packaging is done in ISO Class 8 cleanrooms. By preventing decay, nitrogen washing increases the shelf life of food.

Process paperwork includes master batch records, validation procedures, and SOP guides that can be used for checks by regulators.

Packaging & Logistics Solutions

Standard Packaging

25kg fiber drums with double food-grade polyethylene liners, sealed under vacuum or nitrogen atmosphere. Each drum includes:

• Tamper-evident seal
• Lot number and production/expiry dates
• Handling instructions in English/Chinese
• Desiccant packet (food-grade silica gel)

Custom Packaging Options

Flexible formats to match your production scale:

• 1kg foil bags – Ideal for sampling or small-batch production
• 5kg/10kg aluminum bags – Mid-size manufacturing runs
• 500kg bulk containers – For large-scale industrial users
• Private labeling available – Your brand, our manufacturing

Storage & Stability

• Optimal conditions: 15-25°C, relative humidity <60%
• Photostability: Store away from direct sunlight (amber glass/opaque containers recommended for long-term storage)
• Oxygen sensitivity: Reseal containers promptly after opening; consider nitrogen flushing for extended use
• Validated shelf life: 24 months at 25°C/60% RH (real-time stability data available)

Global Shipping Capabilities

Express courier (1-2 kg samples):

DHL, FedEx, UPS – 5-7 business days to major cities

Air freight (20-500 kg orders):

7-12 days door-to-door with customs clearance support

Sea freight (500+ kg bulk orders):

Cost-effective for large volumes; 25-35 days depending on destination port

Logistics partners: We work with top-rated freight forwarders experienced in botanical ingredient handling. Temperature-controlled shipping available for sensitive climates.

Documentation package includes:

• Commercial invoice
• Packing list
• Certificate of Analysis (COA)
• Material Safety Data Sheet (MSDS)
• Free sale certificate
• Country-specific regulatory documents upon request

Why Leading Brands Choose Zhenhuacui

1. Decade-Proven Manufacturing Reliability

Since 2013, we've worked with more than 200 brands. We have never had to return a product, which shows that we are committed to quality uniformity.

2. Innovation-Focused R&D Infrastructure

Our 18-person R&D team, spends 60% of the company's money on:

• Development of custom formulations
• Testing for stability and compatibility
• Research on improving bioavailability

Recently, they came up with a grade that dissolves in water in 30 seconds (patent pending).

3. Unmatched Supply Flexibility

• MOQ is only 1 kg, so you can try our quality before you buy a lot of it.
• 500 kg or more in stock—Ship to normal specs in 48 hours
• Production that can be scaled up or down—take orders ranging from 1 kg samples to 20-ton yearly contracts

In 20 days, you can get custom specs for non-standard particle shapes or ratios.

4. Speed-to-Market Advantage

• Standard items: 10 days to deliver
• 20 business days for custom formulas, which includes testing.
• Fast service: 7-day rush sales are possible
• Response time for technical support: 24 hours by email, right away through WeChat and WhatsApp

5. Full-Service OEM/ODM Capabilities

In addition to raw materials, we also make finished goods:

• Tablets (with instant or long-term release)
• Gelatin capsules for vegetarians
• Gummies made from pectin and gelatin
• Blends of powder (stick packs, jars)
• Extracts in liquid form (glycerin or alcohol-based)

Having one source for all of your products makes things easier and increases your profit margins.

6. Transparent Quality Documentation

Each package comes with:

• Documentation (COA) that shows test results
• Verification by a third party lab (SGS, Eurofins) is provided upon request.
• Stability data to back up shelf-life claims
• Regulatory paperwork that is made for your business
• Certificates of kosherness or halalness (if needed)

7. Regulatory Expertise Across Markets

Our legal team helps with regulations for the following:

• USA: FDA registration, GRAS status, and NDI reports; EU: new food applications and EFSA paperwork;
• Australia: Help with TGA listings (ARTG)
• Canada: applications for NPN and NHP
• Southeast Asia: Import licenses for each country

Our Teams & Exhibitions

FAQ

Q: What distinguishes 10% crude powder from 98% standardised extract?

A: To attain the same active dosage as our 98% extract, crude powder (5-15% Dihydromyricetin) needs 6-8 times more material. This increases capsule/tablet count, formulation costs, and occasional batch potency. Our pharmaceutical-grade standardisation ensures precise dosage and lower serving sizes—essential for consumer compliance.

Q: Can this ingredient withstand high-temperature food processing?

A: Yes. Accelerated stability testing shows <3% deterioration at 120°C for 30 minutes, indicating compatibility with:

• Pasteurisation (72-85°C)
• Brief 150°C exposure hard candy making
• Heat from tablet compression
• Encapsulated ingredients can be baked at 180°C.
• Request full thermal stability reports.

Q: Does this work for vegan and allergen-free products?

A: Yes. The ingredient:

• No animal products or processing assistance | 100% plant-derived
• Free of 28 main allergens per FDA standards
• Non-GMO certified
• Suitable for kosher/halal formulations

Ideal for clean-label and inclusive product positioning.

Q: What is your custom specification lead time?

A:

• Stock products (98% standard): 10 days production+shipping.
• 20 working days, including testing, for custom concentrations (80%, 90%).
• Custom blends: 20-25 days, complexity varies.
• Rush orders: 7-10 days with charge (capacity permitting).

Q: Do you offer formulation and technical advice?

A: Our R&D team provides:

• Recommended dosages from research and customer case studies
• Stability testing in your formulation matrix
• Other ingredient compatibility studies
• Optimising solubility for difficult applications
• Health claim and documentation regulations

This consultation is free for orders above 1000kg.

Q: What paperwork included with each shipment?

A: The standard package includes:

• Analysis COA with test results
• MSDS
• Sheet specifications
• If appropriate, Kosher/Halal certifications
• Non-GMO claim
• An allergen statement

Additional papers upon request:

• SGS/Eurofins lab testing
• Stability study data
• Batch-certified organic certifications
• Country-specific import licenses
• Free sale certificate 

Q: Do you provide customised botanical blends?

A: Our OEM/ODM services include:

• Custom mixing with complementing components (monk fruit, milk thistle, liquorice, chrysanthemum, hovenia dulcis)
• Synergistic formulation from ancient usage and current research
• Tablet, pill, gummy, and powder production
• Branded private labelling

We've created 50+ bespoke formulae for customers, from two-ingredient mixes to multi-botanical wellness solutions.

Q: How do you maintain batch quality?

A: Our quality system includes:

• Contract organic farms (no wild-harvest variability)
• Incoming raw material testing (ID, potency, contaminants)
• Validated, documented extraction techniques
• Three HPLC tests (process, pre-release, stability)

Batch-to-batch Dihydromyricetin concentration fluctuation is generally <2%.

Q: Can I acquire samples and what is your minimum order quantity?

A:

• The stock MOQ is 1 kilogram, ideal for first testing.
• Free 20-50g samples for approved purchasers (freight collect).
• Standard-priced 100-500g samples by goods gather
• Volume savings start at 100kg.

We may consider smaller trial batches for bespoke recipes, which have a 50kg MOQ.

Get Started with Premium Ampelopsis Grossedentata Extract

Immediate next steps:

1. Request your free sample (20-50g) to evaluate quality firsthand
2. Download technical data sheet with full specifications and stability reports
3. Schedule a formulation consultation with our R&D team
4. Get a custom quote for your specific volume requirements

Ready to secure your supply? Current inventory levels support immediate fulfillment for orders up to 500kg. Lock in competitive pricing before our next production cycle.

Contact Us

Do you have more questions about Ampelopsis Grossedentata Leaf Powder?

Email: plantex@asianbios.com​​​​​​​